o4 cy7 Search Results


95
Miltenyi Biotec o4 cy7
O4 Cy7, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Lumiprobe cy7 nhs ester
(A) Representative IVIS images of Cy5-siRNA/NP loaded hydrogels and <t>Cy7-labeled</t> hydrogels at right femur fractures over time. 1 nmole of Cy5-siRNA was injected at fracture sites (free siRNA/NPs) or embedded into 20 µl 4 kDa PEG hydrogels and implanted at fractures. Hydrogel prepared using 4 kDa Cy7-labeled PEG was also implanted at fractures. siRNA and hydrogels were co-localized at fractures for ~21 days, whereas free siRNA/NP dispersed from injection sites rapidly. (B) Quantification of siRNA/NP and hydrogel localization from IVIS imaging. Data showed the total radiant efficiency of drawn region of interest (ROI) in IVIS images normalized to day 0. Mean ± STDEV, n = 6. (C) Fold change gene expression of Wwp1 14 days after treatment of siRNA hydrogels (0.02 nmole siRNA in 20 µl hydrogels, dose of siRNA 0.013 mg/kg). (D) Fold change gene expression of Runx2, (E) OC, (F) ALP, and (G) Col1a1 14 days after treatments. Mean ± STDEV, n = 8. For (C) to (G), statistical significance was evaluated using one-way ANOVA with Tukey’s post-hoc analysis. *, #, $, %, &, and δ p < 0.05 versus no treatment, hydrogel only, Wwp1 siRNA + gel, scrambled siRNA/NP + gel, Wwp1 siRNA/NP injection, and no fracture, respectively.
Cy7 Nhs Ester, supplied by Lumiprobe, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cy7 nhs ester/product/Lumiprobe
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cy7 nhs ester - by Bioz Stars, 2026-04
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97
Miltenyi Biotec 5741s o4 cy7 miltenyi rrid ab 2733887 cd133 apc thermo rrid ab 823120 anti glast biotin miltenyi
(A) Representative IVIS images of Cy5-siRNA/NP loaded hydrogels and <t>Cy7-labeled</t> hydrogels at right femur fractures over time. 1 nmole of Cy5-siRNA was injected at fracture sites (free siRNA/NPs) or embedded into 20 µl 4 kDa PEG hydrogels and implanted at fractures. Hydrogel prepared using 4 kDa Cy7-labeled PEG was also implanted at fractures. siRNA and hydrogels were co-localized at fractures for ~21 days, whereas free siRNA/NP dispersed from injection sites rapidly. (B) Quantification of siRNA/NP and hydrogel localization from IVIS imaging. Data showed the total radiant efficiency of drawn region of interest (ROI) in IVIS images normalized to day 0. Mean ± STDEV, n = 6. (C) Fold change gene expression of Wwp1 14 days after treatment of siRNA hydrogels (0.02 nmole siRNA in 20 µl hydrogels, dose of siRNA 0.013 mg/kg). (D) Fold change gene expression of Runx2, (E) OC, (F) ALP, and (G) Col1a1 14 days after treatments. Mean ± STDEV, n = 8. For (C) to (G), statistical significance was evaluated using one-way ANOVA with Tukey’s post-hoc analysis. *, #, $, %, &, and δ p < 0.05 versus no treatment, hydrogel only, Wwp1 siRNA + gel, scrambled siRNA/NP + gel, Wwp1 siRNA/NP injection, and no fracture, respectively.
5741s O4 Cy7 Miltenyi Rrid Ab 2733887 Cd133 Apc Thermo Rrid Ab 823120 Anti Glast Biotin Miltenyi, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/5741s o4 cy7 miltenyi rrid ab 2733887 cd133 apc thermo rrid ab 823120 anti glast biotin miltenyi/product/Miltenyi Biotec
Average 97 stars, based on 1 article reviews
5741s o4 cy7 miltenyi rrid ab 2733887 cd133 apc thermo rrid ab 823120 anti glast biotin miltenyi - by Bioz Stars, 2026-04
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90
Miltenyi Biotec o4 apc-cy7
(A) Representative IVIS images of Cy5-siRNA/NP loaded hydrogels and <t>Cy7-labeled</t> hydrogels at right femur fractures over time. 1 nmole of Cy5-siRNA was injected at fracture sites (free siRNA/NPs) or embedded into 20 µl 4 kDa PEG hydrogels and implanted at fractures. Hydrogel prepared using 4 kDa Cy7-labeled PEG was also implanted at fractures. siRNA and hydrogels were co-localized at fractures for ~21 days, whereas free siRNA/NP dispersed from injection sites rapidly. (B) Quantification of siRNA/NP and hydrogel localization from IVIS imaging. Data showed the total radiant efficiency of drawn region of interest (ROI) in IVIS images normalized to day 0. Mean ± STDEV, n = 6. (C) Fold change gene expression of Wwp1 14 days after treatment of siRNA hydrogels (0.02 nmole siRNA in 20 µl hydrogels, dose of siRNA 0.013 mg/kg). (D) Fold change gene expression of Runx2, (E) OC, (F) ALP, and (G) Col1a1 14 days after treatments. Mean ± STDEV, n = 8. For (C) to (G), statistical significance was evaluated using one-way ANOVA with Tukey’s post-hoc analysis. *, #, $, %, &, and δ p < 0.05 versus no treatment, hydrogel only, Wwp1 siRNA + gel, scrambled siRNA/NP + gel, Wwp1 siRNA/NP injection, and no fracture, respectively.
O4 Apc Cy7, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Miltenyi Biotec o4 apc-cy7 (1:100)
(A) Representative IVIS images of Cy5-siRNA/NP loaded hydrogels and <t>Cy7-labeled</t> hydrogels at right femur fractures over time. 1 nmole of Cy5-siRNA was injected at fracture sites (free siRNA/NPs) or embedded into 20 µl 4 kDa PEG hydrogels and implanted at fractures. Hydrogel prepared using 4 kDa Cy7-labeled PEG was also implanted at fractures. siRNA and hydrogels were co-localized at fractures for ~21 days, whereas free siRNA/NP dispersed from injection sites rapidly. (B) Quantification of siRNA/NP and hydrogel localization from IVIS imaging. Data showed the total radiant efficiency of drawn region of interest (ROI) in IVIS images normalized to day 0. Mean ± STDEV, n = 6. (C) Fold change gene expression of Wwp1 14 days after treatment of siRNA hydrogels (0.02 nmole siRNA in 20 µl hydrogels, dose of siRNA 0.013 mg/kg). (D) Fold change gene expression of Runx2, (E) OC, (F) ALP, and (G) Col1a1 14 days after treatments. Mean ± STDEV, n = 8. For (C) to (G), statistical significance was evaluated using one-way ANOVA with Tukey’s post-hoc analysis. *, #, $, %, &, and δ p < 0.05 versus no treatment, hydrogel only, Wwp1 siRNA + gel, scrambled siRNA/NP + gel, Wwp1 siRNA/NP injection, and no fracture, respectively.
O4 Apc Cy7 (1:100), supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/o4 apc-cy7 (1:100)/product/Miltenyi Biotec
Average 90 stars, based on 1 article reviews
o4 apc-cy7 (1:100) - by Bioz Stars, 2026-04
90/100 stars
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N/A
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation.
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N/A
FOXO1 is a transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the
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Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and
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FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced
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These genes encode a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in
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N/A
These genes encode a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in
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N/A
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in
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Image Search Results


(A) Representative IVIS images of Cy5-siRNA/NP loaded hydrogels and Cy7-labeled hydrogels at right femur fractures over time. 1 nmole of Cy5-siRNA was injected at fracture sites (free siRNA/NPs) or embedded into 20 µl 4 kDa PEG hydrogels and implanted at fractures. Hydrogel prepared using 4 kDa Cy7-labeled PEG was also implanted at fractures. siRNA and hydrogels were co-localized at fractures for ~21 days, whereas free siRNA/NP dispersed from injection sites rapidly. (B) Quantification of siRNA/NP and hydrogel localization from IVIS imaging. Data showed the total radiant efficiency of drawn region of interest (ROI) in IVIS images normalized to day 0. Mean ± STDEV, n = 6. (C) Fold change gene expression of Wwp1 14 days after treatment of siRNA hydrogels (0.02 nmole siRNA in 20 µl hydrogels, dose of siRNA 0.013 mg/kg). (D) Fold change gene expression of Runx2, (E) OC, (F) ALP, and (G) Col1a1 14 days after treatments. Mean ± STDEV, n = 8. For (C) to (G), statistical significance was evaluated using one-way ANOVA with Tukey’s post-hoc analysis. *, #, $, %, &, and δ p < 0.05 versus no treatment, hydrogel only, Wwp1 siRNA + gel, scrambled siRNA/NP + gel, Wwp1 siRNA/NP injection, and no fracture, respectively.

Journal: Biomaterials

Article Title: Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing

doi: 10.1016/j.biomaterials.2017.06.001

Figure Lengend Snippet: (A) Representative IVIS images of Cy5-siRNA/NP loaded hydrogels and Cy7-labeled hydrogels at right femur fractures over time. 1 nmole of Cy5-siRNA was injected at fracture sites (free siRNA/NPs) or embedded into 20 µl 4 kDa PEG hydrogels and implanted at fractures. Hydrogel prepared using 4 kDa Cy7-labeled PEG was also implanted at fractures. siRNA and hydrogels were co-localized at fractures for ~21 days, whereas free siRNA/NP dispersed from injection sites rapidly. (B) Quantification of siRNA/NP and hydrogel localization from IVIS imaging. Data showed the total radiant efficiency of drawn region of interest (ROI) in IVIS images normalized to day 0. Mean ± STDEV, n = 6. (C) Fold change gene expression of Wwp1 14 days after treatment of siRNA hydrogels (0.02 nmole siRNA in 20 µl hydrogels, dose of siRNA 0.013 mg/kg). (D) Fold change gene expression of Runx2, (E) OC, (F) ALP, and (G) Col1a1 14 days after treatments. Mean ± STDEV, n = 8. For (C) to (G), statistical significance was evaluated using one-way ANOVA with Tukey’s post-hoc analysis. *, #, $, %, &, and δ p < 0.05 versus no treatment, hydrogel only, Wwp1 siRNA + gel, scrambled siRNA/NP + gel, Wwp1 siRNA/NP injection, and no fracture, respectively.

Article Snippet: In vivo localization of siRNA/NP hydrogels Cyanine7 (Cy7)-PEG-acrylate (Cy7-PEG-AC) was synthesized using Cy7 NHS ester (C 41 H 48 ClN 3 O 4 , Lumiprobe) and acrylate-PEG-amine (Ac-PEG-NH 2 , MW 3.4 kDa, Creative PEGWorks) via carbodiimide chemistry.

Techniques: Labeling, Injection, Imaging, Gene Expression